Mankind has made huge strides in healthcare over the last 100 years, due to a combination of enormous funding, increased expenditure on research and technology and an accumulation of shared knowledge which has allowed us to combat even the most deadly diseases. In the developed world we no longer have to worry about being wiped out by diseases such as the Black Death which eviscerated huge swathes of the European population centuries ago.

However there are some medical problems that are so rare and unusual that they’ve received little attention, and since there is little profit opportunity in combating them (due to their rarity), doctors can do little to effect a cure if you’re unfortunate enough to suffer from them.

Here we present the 10 most unusual and weird medical conditions that you have probably never heard of. Some of them are so odd that you’ll be scratching your head and wondering if they’re actually made up. Believe it or not, all of these unusual medical problems do actually exist.

10. Alien Hand Syndrome

10 alien hand

Alien Hand Syndrome is another syndrome which affects the brain. The patient who suffers has problems controlling their hands, so that they appear to have a life of their own. Thus, they often grab, grip and swat without even realizing they are doing it. This of course makes it very difficult to exert proper motor control, leading to a real reduction in their quality of life.

The cause of this strange and disturbing syndrome is thought to be the result of surgical operations on parts of the brain that control arm and hand movement (usually in an attempt to fix epilepsy, stroke or brain injury).

There is unfortunately no cure.